Consult a health care practitioner prior to use if you have human herpes virus, sickle cell anemia, or are taking antihypertensives, cyclosporine, estrogens, birth control medications, medroxyprogesterone, norethindrone, nitrates, potassium-increasing drugs, sildenafil, xylitol, and/or aminophylline. Do not use if you have had a myocardial infarction (heart attack), or if you have gout, decreased platelet count, elevated blood-urea-nitrogen, serum creatine and creatinine, delayed menses, asthma, or are pregnant or breastfeeding.