Genestra HMF Intensive (Shelf-Stable) 25 Veg Capsules

Proprietary human strain probiotic for extra daily support

• Provides 25 billion CFU per capsule
• Probiotics to supplement the normal intestinal microbiota following antibiotic therapy
• Helps improve symptoms of irritable bowel syndrome (IBS) such as bloating, satisfaction with bowel habits, and days with pain within 6 weeks
• No refrigeration necessary
• Potency guaranteed through expiration

HMF^® Intensive provides a combination of human strain probiotics clinically demonstrated to supplement the normal intestinal microbiota following antibiotic therapy and significantly reduce symptoms of irritable bowel syndrome (IBS) in adults and children over 11 years. Although the microflora composition in the gut is relatively steady, it can be altered by diet, stress, age, and medication use.¹ Clinical trials have found that supplementation with HMF^® Intensive’s probiotic formula supported gastrointestinal health and helped decrease the degree of microflora disruption associated with antibiotic intake.^2,3 Probiotic supplementation with 25 billion CFU Lactobacillus acidophilus (CUL-60 and CUL-21), Bifidobacterium bifidum (CUL-20), and Bifidobacterium animalis subsp. lactis (CUL-34) has also been associated with a lower incidence and severity of GI symptoms in marathon runners.⁴ Additionally, a clinical trial reported that daily supplementation with this probiotic formula for eight weeks significantly improved six measures of IBS symptoms (symptom severity score, abdominal pain, bloating, days with pain, satisfaction with bowel habits, and quality of life).⁵ HMF^® Intensive contributes to a natural healthy gut flora with a concentrated dose of 25 billion CFU per capsule. This convenient shelf-stable format has potency guaranteed through expiration and may improve patient compliance.

^Ingredients:

^{EACH CAPSULE CONTAINS:}

• ^{Probiotic Consortium ...................................... 15 billion CFU}
• ^{Lactobacillus acidophilus (CUL-60 & CUL-21) ................. 10 billion CFU}
• ^{Lactobacillus gasseri (CUL-09) ............................ 2.5 billion CFU}
• ^{Bifidobacterium animalis subsp. lactis(CUL-34) & Bifidobacterium bifidum (CUL-20) ...................... . 2.5 billion CFU}
• ^{PACRAN® Cranberry (Vaccinium macrocarpon) Fruit Extract (50:1) ..... 250 mg 12.5 g Fresh Fruit Equivalent}

^{Non-Medicinal Ingredients: Hypromellose, cellulose, sunflower lecithin, silica. Ingredients used to maintain the viability of probiotics (dipotassium phosphate, monopotassium phosphate, trehalose, sucrose, sodium ascorbate).}

^Dosing:

Recommended Dose: Adults, Adolescents and Children (6 years and older): Take 1 capsule daily with a meal, at least 2 to 3 hours before or after taking antibiotics, or as recommended by your healthcare practitioner.

^Cautions:

Risk Information: Do not use this product if you have an immune-compromised condition. Consult your healthcare practitioner prior to use if you are experiencing nausea, fever, vomiting, bloody diarrhea or severe abdominal pain. Stop using and consult your healthcare practitioner if symptoms of digestive upset occur, worsen or persist beyond 3 days

REFERENCES
1. Hudson T. Altern Complement Ther. 2006 Dec;12(6):297-302.
2. Howell AB. Mol Nutr Food Res. 2007 Jun;51(6):732-7.
3. Sengupta K, V Alluri K, Golakoti T, V Gottumukkala G, Raavi J, et al. Current Bioactive Compounds. 2011 Mar;7(1):39-46.
4. Fromentin E, Vostalova J, Vidlar A, Galandakova A, Vrbkova J, et al. FASEB J. 2014 April; 28(1, Suppl 639.4).
5. Seroyal. Data on file.
6. Pavlova SI, Kilic AO, Kilic SS, So JS, Nader-Macias ME, et al. J Appl Microbiol. 2002;92(3): 451-9.